Article
Visceral and ectopic fat are more predictively associated with primary liver cancer than overall obesity from genetic sights: A Mendelian randomization study.
International journal of cancer - 1 Feb 2024
Xu Fei-Qi, Xu Qing-Yun, Zhu Zhang-Ji, Jin Lei, Ye Tai-Wei, Du Cheng-Fei, Gao Zhen-Yu, Huang Xiao-Kun, Zhang Zhe, Jin Li-Ming, Yao Wei-Feng
Abstract excerpt
Several observational studies have reported an association between obesity and primary liver cancer (PLC), while the causality behind this association and the comparison of the risk effects of different obesity indicators on PLC remain unclear. In this study, we performed two-sample Mendelian randomization (MR) analyses to assess the associations of genetically determined liver fat, visceral adipose tissue (VAT),...
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