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Article

Generation of Mt3 Homozygote murine ES cell lines via CRISPR/Cas9 technology.

Stem cell research - 1 Apr 2022

Zhou Huanxin, Sun Hongyan, Rong Zhijiang, Cui Wei

Abstract excerpt

Metallothioneins belong to a superfamily of intracellular metal-binding proteins, have bearing on almost all biochemical processes,include free radical scavenging, apoptosis, regulation of intracellular redox balance, and anti-inflammatory processes. By using a CRISPR/Cas 9 system, we generated Mt3-/- mES line. This cell line has contributed to further investigation of the functions of Mtt3 during early...

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PMID: 35217495
DOI: 10.1016/j.scr.2022.102714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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