Article

The Balance between Life and Death of Cells: Roles of Metallothioneins

2006-01-01

Abstract excerpt

Metallothionein (MT) is a highly conserved, low-molecular-weight, cysteine-rich protein that occurs in 4 isoforms (MT-I to MT-IV), of which MT-I+II are the major and best characterized proteins. This review will focus on mammalian MT-I+II and their functional impact upon cellular survival and death, as seen in two rather contrasting pathological conditions: Neurodegeneration and neoplasms. MT-I+II have analogous f...

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Literature Corpus work: a92cfd06-1b37-5730-8058-2a71912342b7
DOI: 10.1177/117727190600100016

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