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Article

Metallothionein polymorphisms in pathological processes.

Metallomics : integrated biometal science - 1 Jan 2014

Raudenska Martina, Gumulec Jaromir, Podlaha Ondrej, Sztalmachova Marketa, Babula Petr, Eckschlager Tomas, Adam Vojtech, Kizek Rene, Masarik Michal

Abstract excerpt

Metallothioneins (MTs) are a class of metal-binding proteins characterized by a high cysteine content and low molecular weight. MTs play an important role in metal metabolism and protect cells against the toxic effects of radiation, alkylating agents and oxygen free radicals. The evidence that individual genetic characteristics of MTs play an important role in physiological and pathological processes associated...

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PMID: 24068159
DOI: 10.1039/c3mt00132f

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