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Article

Genome-Wide Association Analysis and Genomic Prediction of Thyroglobulin Plasma Levels.

International journal of molecular sciences - 16 Feb 2022

Pleić Nikolina, Babić Leko Mirjana, Gunjača Ivana, Boutin Thibaud, Torlak Vesela, Matana Antonela, Punda Ante, Polašek Ozren, Hayward Caroline, Zemunik Tatijana

Abstract excerpt

Thyroglobulin (Tg) is an iodoglycoprotein produced by thyroid follicular cells which acts as an essential substrate for thyroid hormone synthesis. To date, only one genome-wide association study (GWAS) of plasma Tg levels has been performed by our research group. Utilizing recent advancements in computation and modeling, we apply a Bayesian approach to the probabilistic inference of the genetic architecture of...

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PMID: 35216288
DOI: 10.3390/ijms23042173
PMCID: PMC8876738

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