Article
Chikungunya Virus' High Genomic Plasticity Enables Rapid Adaptation to Restrictive A549 Cells.
Viruses - 28 Jan 2022
De Caluwé Lien, Heyndrickx Leo, Coppens Sandra, Vereecken Katleen, Quiñones-Mateu Miguel E, Merits Andres, Ariën Kevin K, Bartholomeeusen Koen
Abstract excerpt
Chikungunya virus (CHIKV) is an emerging arthropod-borne virus that has spread globally during the last two decades. The virus is mainly transmitted by Aedes aegypti and Aedes albopictus mosquitos and is thus capable of replicating in both human and mosquito cells. CHIKV has a broad tropism in vivo, capable of replicating in various tissues and cell types but largely excluding blood cells. This was reflected in...
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