Article
Correlation of phylogenetic clade diversification and in vitro infectivity differences among Cosmopolitan genotype strains of Chikungunya virus.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2016
Abraham Rachy, Manakkadan Anoop, Mudaliar Prashant, Joseph Iype, Sivakumar Krishnankutty Chandrika, Nair Radhakrishnan Reghunathan, Sreekumar Easwaran
Abstract excerpt
Cosmopolitan genotypes of Chikungunya virus caused the large-scale febrile disease outbreaks in the last decade in Asian and African continents. Molecular analyses of these strains had revealed significant genetic diversification and occurrence of novel mosquito-adaptive mutations. In the present study we looked into whether the genetic diversification has implications in the infectivity phenotype. A detailed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
