Article
Identification of mannose-binding lectin as a mechanism in progressive immunoglobulin A nephropathy.
International journal of clinical and experimental pathology - 1 Jan 2015
Shi Beili, Wang Ling, Mou Shan, Zhang Minfang, Wang Qin, Qi Chaojun, Cao Liou, Che Xiajing, Fang Wei, Gu Leyi, Yan Yucheng, Qian Jiaqi, Ni Zhaohui
Abstract excerpt
Immunoglobulin A nephropathy (IgAN), the pathogenesis of which remained still unclear is one of the leading courses of end-stage renal disease in approximately 50% affected patients. On the basis of several researches, the activation of complement mannose-binding lectin (MBL) pathway might be the underlying mechanism in disease progress. In order to investigate the relationship between MBL pathway and IgAN, we...
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