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Article

Macrophage Phenotype and Fibrosis in Diabetic Nephropathy.

International journal of molecular sciences - 17 Apr 2020

Calle Priscila, Hotter Georgina

Abstract excerpt

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease globally. The primary initiating mechanism in DN is hyperglycemia-induced vascular dysfunction, but its progression is due to different pathological mechanisms, including oxidative stress, inflammatory cells infiltration, inflammation and fibrosis. Macrophages (Mφ) accumulation in kidneys correlates strongly with serum creatinine,...

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Identifiers

PMID: 32316547
DOI: 10.3390/ijms21082806
PMCID: PMC7215738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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