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GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy

9 Aug 2023

Abstract excerpt

Background: Diabetic nephropathy (DN) is one of the most common diabetic complications, which has become the primary cause of end-stage renal disease (ESRD) globally. Macrophage infiltration has been proven vital in the occurrence and development of DN. This study was designed to investigate the hub genes involved in macrophage-mediated inflammation of DN via bioinformatics analysis and experimental validation....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37622120
DOI: 10.3389/fimmu.2023.1127612

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