Article
Genetic diversity of Plasmodium falciparum AMA-1 antigen from the Northeast Indian state of Tripura and comparison with global sequences: implications for vaccine development.
Malaria journal - 22 Feb 2022
Nirmolia Tulika, Ahmed Md Atique, Sathishkumar Vinayagam, Sarma Nilanju P, Bhattacharyya Dibya R, Mohapatra Pradyumna K, Bansal Devendra, Bharti Praveen K, Sehgal Rakesh, Mahanta Jagadish, Sultan Ali A, Narain Kanwar, Patgiri Saurav J
Abstract excerpt
BACKGROUND: Malaria continues to be a major public health problem in the Northeastern part of India despite the implementation of vector control measures and changes in drug policies. To develop successful vaccines against malaria, it is important to assess the diversity of vaccine candidate antigens in field isolates. This study was done to assess the diversity of Plasmodium falciparum AMA-1 vaccine candidate...
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