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DCAF13 promotes breast cancer cell proliferation by ubiquitin inhibiting <i>PERP</i> expression

18 Feb 2022

Abstract excerpt

Abstract Evolutionarily conserved DDB1‐and CUL4‐associated factor 13 (DCAF13) is a recently discovered substrate receptor for the cullin RING‐finger ubiquitin ligase 4 (CRL4) E3 ubiquitin ligase that regulates cell cycle progression. DCAF13 is overexpressed in many cancers, although its role in breast cancer is currently elusive. In this study we demonstrate that DCAF13 is overexpressed in human breast cancer and...

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PMID: 35178836
DOI: 10.1111/cas.15300

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