Article
DCAF13 is associated with pancreatic ductal adenocarcinoma progression and p53-related signaling in TP53-mutant cells.
Biochemical and biophysical research communications - 3 Sept 2026
Fan Xiaofang, Zhao Hengping, Wu Bin, Lv Yichen, Chen Wei, Chen Qi, Hu Lingyu, Yu Shenjie, Wang Jiale, He Yahui, Yu Jiaqi
Abstract excerpt
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with poor prognosis. DDB1 and CUL4 associated factor 13 (DCAF13) has been implicated in tumor progression, but its clinical relevance and biological function in PDAC remain unclear. METHODS: Public databases (GEPIA2 and Kaplan-Meier Plotter) were used to analyze DCAF13 expression and its prognostic value in PDAC. Tumor and...
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