Article
Association of intronic polymorphism rs3773364 A>G in synapsin-2 gene with idiopathic epilepsy.
Synapse (New York, N.Y.) - 1 May 2010
Lakhan Ram, Kalita J, Misra U K, Kumari Ritu, Mittal Balraj
Abstract excerpt
In epilepsy, there is a tendency towards recurrent unprovoked seizures. Seizures result due to the excessive electrical misfiring in the brain between neurons and disturbance in neurotransmitter release. Several gene products affect the behavior of these neurons by regulating neurotransmission via several mechanisms. One such gene, Synapsin-2 (SYN2), involved in synaptogenesis is also reported to regulate the...
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