Article
RORA gene rs12912233 and rs880626 polymorphisms and their interaction with SCN1A rs3812718 in the risk of epilepsy: a case-control study in Malaysia.
Genomics - 1 Apr 2015
Haerian Batoul Sadat, Sha'ari Hidayati Mohd, Tan Hui Jan, Fong Choong Yi, Wong Sau Wei, Ong Lai Choo, Raymond Azman Ali, Tan Chong Tin, Mohamed Zahurin
Abstract excerpt
RAR-related orphan receptors A (RORA) and B (RORB) and voltage-gated sodium channel type 1 (SCN1A) genes play critical roles in the regulation of the circadian clock. Evidence has shown an association of RORA and RORB polymorphisms with susceptibility to autism and depression. Hence, we tested the association of RORA rs12912233, rs16943429, rs880626, rs2290430, and rs12900948; RORB , ,...