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Article

Discovery of SIRT7 Inhibitor as New Therapeutic Options Against Liver Cancer

31 Jan 2022

Abstract excerpt

Optimal therapeutic strategies for liver cancer patients remain challenging due to the high recurrence rate after surgical resection and chemotherapy resistance. Emerging evidence has shown that epigenetic factor SIRT7 is involved in various aspects of cancer biology, while inactive SIRT7 reverses human cancer phenotype and suppresses tumor growth. In the present study, we predicted the SIRT7 structure by using...

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PMID: 35174171
DOI: 10.3389/fcell.2021.813233

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