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Article

SIRT7 as a context-dependent biomarker and therapeutic target: Insights from a pan-cancer study.

PloS one - 1 Jan 2026

Islam K M Tanjida, Mahmud Shahin

Abstract excerpt

SIRT7 is a member of the sirtuin family and has emerged as a crucial player in cancer biology, with a multifaceted role in both tumor-promoting and tumor-suppressing activities. Despite its importance in connecting NAD+ metabolism with transcriptional regulation, a systematic analysis across multiple cancer types remains underexplored, thereby limiting our understanding of its prognostic value, mutational impact,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41642899
DOI: 10.1371/journal.pone.0342269
PMCID: PMC12875470

Genes

SIRT7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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