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Article

Clonal hematopoiesis and cardiovascular diseases: role of JAK2V617F.

Journal of cardiology - 1 Jan 2023

Misaka Tomofumi, Kimishima Yusuke, Yokokawa Tetsuro, Ikeda Kazuhiko, Takeishi Yasuchika

Abstract excerpt

Bone marrow-derived hematopoietic and immune cells play important roles in the onset and progression of cardiovascular diseases. Recent genetic analyses have discovered that clonal expansion of bone marrow hematopoietic stem/progenitor cells carrying somatic gene mutations is common and is increasing with age in healthy individuals who do not show any hematologic disorders, termed as clonal hematopoiesis. It is...

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Source

Identifiers

PMID: 35165011
DOI: 10.1016/j.jjcc.2022.02.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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