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Article

Mutational landscape of blast phase myeloproliferative neoplasms (MPN-BP) and antecedent MPN.

International review of cell and molecular biology - 1 Jan 2022

Pasca Sergiu, Chifotides Helen T, Verstovsek Srdan, Bose Prithviraj

Abstract excerpt

Myeloproliferative neoplasms (MPN) have an inherent tendency to evolve to the blast phase (BP), characterized by ≥20% myeloblasts in the blood or bone marrow. MPN-BP portends a dismal prognosis and currently, effective treatment modalities are scarce, except for allogeneic hematopoietic stem cell transplantation (allo-HSCT) in selected patients, particularly those who achieve complete/partial remission. The...

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Identifiers

PMID: 35153007
DOI: 10.1016/bs.ircmb.2021.02.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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