Blast phase myeloproliferative neoplasm: contemporary review and 2024 treatment algorithm.

Abstract excerpt

Leukemic transformation in myeloproliferative neoplasms (MPN), also referred to as "blast-phase MPN", is the most feared disease complication, with incidence estimates of 1-4% for essential thrombocythemia, 3-7% for polycythemia vera, and 9-13% for primary myelofibrosis. Diagnosis of MPN-BP requires the presence of ≥20% circulating or bone marrow blasts; a lower level of excess blasts (10-19%) constitutes...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Blast Crisis
• Share to Chronic Disease
• Share to Mutation