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Article

Hitting the brakes on accelerated and blast-phase myeloproliferative neoplasms: current and emerging concepts.

Hematology. American Society of Hematology. Education Program - 9 Dec 2022

Bewersdorf Jan Philipp, Rampal Raajit K

Abstract excerpt

The BCR-ABL-negative myeloproliferative neoplasms (MPNs) have a variable risk of progressing to accelerated- or blast-phase MPN (MPN-AP/MPN-BP), defined by the presence of 10% to 19% and more than or equal to 20% myeloid blasts in the peripheral blood or bone marrow, respectively. The molecular processes underlying the progression to MPN-AP/MPN-BP are becoming increasingly understood with the acquisition of...

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Identifiers

PMID: 36485103
DOI: 10.1182/hematology.2022000341
PMCID: PMC9820986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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