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Article

Contribution of common and rare genetic variants in CEP72 on vincristine-induced peripheral neuropathy in brain tumour patients.

British journal of clinical pharmacology - 1 Jul 2022

Klumpers Marije J, Brand Annouk C A M, Hakobjan Marina, Gattuso Giovanna, Schiavello Elisabetta, Terenziani Monica, Massimino Maura, Gidding Corrie E M, Guchelaar Henk-Jan, Te Loo D Maroeska W M, Coenen Marieke J H

Abstract excerpt

AIMS: Studies implicated a role for a genetic variant in CEP72 in vincristine-induced peripheral neuropathy. This study aims to evaluate this association in a cohort of brain tumour patients, to perform a cross-disease meta-analysis and explore the protein-coding region of CEP72. METHODS: In total, 104 vincristine-treated brain tumour patients were genotyped for CEP72 rs924607, and sequenced for the...

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Identifiers

PMID: 35150001
DOI: 10.1111/bcp.15267
PMCID: PMC9313903

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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