Article
Association Between the CEP72 Genotype and Chemotherapy-Induced Peripheral Neuropathy Severity in Young Adults Receiving Vincristine or Paclitaxel.
Oncology nursing forum - 18 Aug 2025
Knoerl Robert, Mazzola Emanuele, Pazyra-Murphy Maria F, Frazier Lindsay, Freeman Roy, Hammer Marilyn J, LaCasce Ann S, Ligibel Jennifer, Luskin Marlise R, Berry Donna L, Segal Rosalind A
Abstract excerpt
OBJECTIVES: To determine the relationship between chemotherapy-induced peripheral neuropathy (CIPN) severity and centrosomal protein 72 (CEP72) genotype in young adults receiving paclitaxel or vincristine. SAMPLE & SETTING: 50 young adults aged 21-39 years who were expected to receive a cumulative dose of at least 7 mg vincristine or 700 mg/m2 paclitaxel for the treatment of cancer were recruited from Dana-Farber...
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