Article
The FCGR2A rs1801274 polymorphism was associated with the risk of death among COVID-19 patients.
Clinical immunology (Orlando, Fla.) - 1 Mar 2022
López-Martínez Rocío, Albaiceta Guillermo M, Amado-Rodríguez Laura, Cuesta-Llavona Elías, Gómez Juan, García-Clemente Marta, Vázquez-Coto Daniel, Alvarez Victoria, Coto Eliecer
Abstract excerpt
Polymorphisms of Fcγ receptors have been associated with variable responses to infections. We determined the association of functional polymorphisms rs1801274 in the FCGR2A and rs396991 in the FCGR3A with COVID-19 severity. This study involved 453 patients with severe COVID-19, in which the FCGR2A rs1801274 G-allele (131-Arg) was significantly associated with death (p = 0.02, OR = 1.47). This effect was...
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