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Article

Association between MASP2 gene polymorphisms and susceptibility to Covid-19 in Iranian patients: a case-control study.

BMC infectious diseases - 24 Oct 2025

Jabbari Maryam, Ghaffari Hadi, Ghaffari Kazem, Khosravi Mersedeh, Latifi Zeinab, Moradi-Hasanabad Amin, Ghasemi Ali

Abstract excerpt

BACKGROUND: Coronavirus disease 2019 (Covid-19) has emerged as a significant public health concern and is widespread across numerous nations. Recent studies have shown that genetic and host immune factors can influence the severity of Covid-19 disease. For example, research has shown that gene polymorphisms in inflammatory pathways and the complement system can play an important role in susceptibility to the...

Topics

Humans
Mannose-Binding Protein-Associated Serine Proteases
COVID-19
Case-Control Studies
Iran
Genetic Predisposition to Disease
Female
Polymorphism, Single Nucleotide
Male
Adult

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

SARS-CoV-2

Genotype

Gene Frequency

Source

Open in PubMed Open full text

Identifiers

PMID: 41136953
DOI: 10.1186/s12879-025-11866-7
PMCID: PMC12553226

Genes

MASP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-41136953-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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