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Article

Improving neuroblastoma risk prediction through a polygenic risk score derived from genome-wide association study-identified loci

1 Jan 2025

Abstract excerpt

Objective: Neuroblastoma is the most common extracranial solid tumor in children and has complex genetic underpinnings. Previous genome-wide association studies (GWASs) have identified many loci associated with neuroblastoma susceptibility; however, their application in risk prediction for Chinese children has not been systematically explored. This study seeks to enhance neuroblastoma risk prediction by...

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PMID: 40078563
DOI: 10.21147/j.issn.1000-9604.2025.01.01

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