Common variations in BARD1 influence susceptibility to high-risk neuroblastoma.

doi:10.1038/ng.374

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Article

Common variations in BARD1 influence susceptibility to high-risk neuroblastoma.

Nature genetics - 1 Jun 2009

Capasso Mario, Devoto Marcella, Hou Cuiping, Asgharzadeh Shahab, Glessner Joseph T, Attiyeh Edward F, Mosse Yael P, Kim Cecilia, Diskin Sharon J, Cole Kristina A, Bosse Kristopher, Diamond Maura, Laudenslager Marci, Winter Cynthia, Bradfield Jonathan P, Scott Richard H, Jagannathan Jayanti, Garris Maria, McConville Carmel, London Wendy B, Seeger Robert C, Grant Struan F A, Li Hongzhe, Rahman Nazneen, Rappaport Eric, Hakonarson Hakon, Maris John M

Abstract excerpt

We conducted a SNP-based genome-wide association study (GWAS) focused on the high-risk subset of neuroblastoma. As our previous unbiased GWAS showed strong association of common 6p22 SNP alleles with aggressive neuroblastoma, we restricted our analysis here to 397 high-risk cases compared to 2,043 controls. We detected new significant association of six SNPs at 2q35 within the BARD1 locus (P(allelic) = 2.35 x...

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Identifiers

PMID: 19412175
DOI: 10.1038/ng.374
PMCID: PMC2753610

Genes

BARD1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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