Article

A genome-wide association study in Chinese children identifies and functionally validates 5q31.1 as a neuroblastoma susceptibility locus

2025-08-13

Abstract excerpt

<h4>Background: </h4> Neuroblastoma, the most common extracranial solid tumor in children, exhibits considerable clinical heterogeneity influenced by genetic predisposition. While genome-wide association studies (GWAS) in European populations have identified eight susceptibility loci, the genetic basis of neuroblastoma in East Asian populations remains poorly understood. <h4>Methods:</h4> We conducted the first GW...

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Literature Corpus work: fee10832-61f5-52bc-a98d-cb7107ef6e0b
DOI: 10.1101/2025.08.11.25333455

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