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Article

Celiac disease: From genetics to epigenetics.

World journal of gastroenterology - 28 Jan 2022

Gnodi Elisa, Meneveri Raffaella, Barisani Donatella

Abstract excerpt

Celiac disease (CeD) is a multifactorial autoimmune disorder spread worldwide. The exposure to gluten, a protein found in cereals like wheat, barley and rye, is the main environmental factor involved in its pathogenesis. Even if the genetic predisposition represented by HLA-DQ2 or HLA-DQ8 haplotypes is widely recognised as mandatory for CeD development, it is not enough to explain the total predisposition for the...

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Identifiers

PMID: 35125829
DOI: 10.3748/wjg.v28.i4.449
PMCID: PMC8790554

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