Article
Peripheral Transport Proteins Were Associated with 4-Year Cognitive Decline in APOE ɛ4 Non-Carriers: A Longitudinal, Population-Based Study.
Journal of Alzheimer's disease : JAD - 1 Jan 2022
Gao Ling, Dang Liangjun, Wei Shan, Hu Ningwei, Gao Fan, Peng Wei, Shang Suhang, Zhao Yi, Chen Chen, Guo Xiaojuan, Huo Kang, Wang Jingyi, Wang Jin, Qu Qiumin
Abstract excerpt
BACKGROUND: Soluble low-density lipoprotein receptor-related protein-1 (sLRP1) and soluble receptor of advanced glycation end products (sRAGE) play major roles in peripheral clearance of amyloid-β (Aβ). OBJECTIVE: To determine the relationship between baseline sLRP1/sRAGE and early cognitive decline in a longitudinal study and explore the possible effect of apolipoprotein E (APOE) on their association. METHODS:...
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