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Article

C-reactive protein, APOE genotype and longitudinal cognitive change in an older population.

Age and ageing - 1 Mar 2014

Lima Thomas A S, Adler Amanda L, Minett Thais, Matthews Fiona E, Brayne Carol, Marioni Riccardo E

Abstract excerpt

BACKGROUND: circulating measures of inflammatory markers, such as C-reactive protein (CRP) have been associated with an increased risk of future cognitive decline. However, the nature of the relationship among the very old (>75 years) is unclear. Cross-sectional evidence suggests that elevated CRP may even be protective in this age group. This study examines these associations longitudinally. METHODS: logistic...

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Source

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Identifiers

PMID: 24305621
DOI: 10.1093/ageing/aft193
PMCID: PMC3927773

Genes

CRP
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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