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Article

Trajectories of inflammatory markers and cognitive decline over 10 years.

Neurobiology of aging - 1 Dec 2014

Metti Andrea L, Yaffe Kristine, Boudreau Robert M, Simonsick Eleanor M, Carnahan Ryan M, Satterfield Suzanne, Harris Tamara B, Ayonayon Hilsa N, Rosano Caterina, Cauley Jane A

Abstract excerpt

We aimed to examine trajectories of inflammatory markers and cognitive decline over 10 years. Cox proportional hazards models were used to examine the association between interleukin-6 and C-reactive protein (CRP) trajectory components (slope, variability, and baseline level) and cognitive decline among 1323 adults, aged 70-79 years in the Health, Aging, and Body Composition Study. We tested for interactions by...

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Identifiers

PMID: 24997674
DOI: 10.1016/j.neurobiolaging.2014.05.030
PMCID: PMC4252870

Genes

CRP
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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