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Effects of HA2 154 deglycosylation and NA V202I mutation on biological property of H5N6 subtype avian influenza virus.

Veterinary microbiology - 1 Mar 2022

Gu Min, Zhao Ying, Ge Zhichuang, Li Yang, Gao Ruyi, Wang Xiaoquan, Hu Jiao, Liu Xiaowen, Hu Shunlin, Peng Daxin, Liu Xiufan

Abstract excerpt

In recent years, clade 2.3.4.4 H5N6 subtype avian influenza virus (AIV) has been predominantly prevalent in poultry flocks in China. During our AIV surveillance in 2018-2019, 6 circulating strains of H5N6 that possess the natural loss of glycosylation site 154 due to N154D mutation in HA2 protein were isolated. In particular, 5 strains simultaneously carried the V202I mutation in NA protein. Based on the paired...

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PMID: 35121305
DOI: 10.1016/j.vetmic.2022.109353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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