Article
Mutations of 127, 183 and 212 residues on the HA globular head affect the antigenicity, replication and pathogenicity of H9N2 avian influenza virus.
Transboundary and emerging diseases - 1 Jul 2022
Fan Menglu, Liang Bing, Zhao Yongzhen, Zhang Yaping, Liu Qingzheng, Tian Miao, Zheng Yiqing, Xia Huizhi, Suzuki Yasuo, Chen Hualan, Ping Jihui
Abstract excerpt
H9N2 avian influenza virus (AIV), one of the predominant subtypes devastating the poultry industry, has been circulating widely in the poultry population and causing huge economic losses. In this study, two H9N2 viruses with similar genetic backgrounds but different antigenicity were isolated from a poultry farm, namely A/chicken/Jiangsu/75/2018 (JS/75) and A/chicken/Jiangsu/76/2018 (JS/76). Sequence analysis...
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