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Article

Influence of β2 adrenergic receptor genotype on longitudinal measures of forced vital capacity in patients with Duchenne muscular dystrophy.

Neuromuscular disorders : NMD - 1 Feb 2022

Kelley Eli F, Cross Troy J, McDonald Craig M, Hoffman Eric P, Bello Luca

Abstract excerpt

The progression of decline in forced vital capacity as percent predicated (FVC%p) is a strong indicator of worsening prognosis in patients with Duchenne muscular dystrophy (DMD). Evidence suggests that ß2 adrenergic (ADRB2) receptors may play a role in determining respiratory function, whereby more functional ADRB2 genotype variants (e.g., Gly16) are associated with improved pulmonary function. The purpose of...

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PMID: 35115229
DOI: 10.1016/j.nmd.2021.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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