Article
Beta2-adrenergic receptor genetic polymorphisms and short-term bronchodilator responses in patients with COPD.
Chest - 1 Nov 2007
Hizawa Nobuyuki, Makita Hironi, Nasuhara Yasuyuki, Betsuyaku Tomoko, Itoh Yoko, Nagai Katsura, Hasegawa Masaru, Nishimura Masaharu
Abstract excerpt
BACKGROUND: COPD is characterized by a persistent airflow limitation that is not fully reversible; thus, the reversibility of airflow limitations in response to a bronchodilator is an important component of COPD. Several studies have established that two common nonsynonymous polymorphisms in the...
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