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Article

Methacholine PC20 in African Americans and whites with asthma with homozygous genotypes at ADRB2 codon 16.

Pulmonary pharmacology & therapeutics - 1 Jun 2013

Blake Kathryn, Cury James D, Hossain Jobayer, Tantisira Kelan, Wang Jianwei, Mougey Edward, Lima John

Abstract excerpt

BACKGROUND: African Americans have worse asthma outcomes compared to whites. Adrenoceptor beta 2, surface gene (ADRB2) Gly16Arg genotypes have been associated with β2-agonist bronchodilator response, asthma exacerbation rate, response to methacholine, and lung function decline but not specifically in African Americans. OBJECTIVE: We sought to compare the provocative concentration of methacholine that causes a 20%...

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Source

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Identifiers

PMID: 23384627
DOI: 10.1016/j.pupt.2013.01.009
PMCID: PMC3624039

Genes

ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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