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Phenotypic and genomic analysis reveals Riemerella anatipestifer as the potential reservoir of tet(X) variants

21 Oct 2021

Abstract excerpt

BACKGROUND: Tigecycline is regarded as one of the last-resort antimicrobials clinically. Emergence of plasmid-mediated tet(X) undermines such an important drug. However, the origins of tet(X) remain largely unexplored. METHODS: Riemerella anatipestifer strains were characterized by PCR, antimicrobial susceptibility testing, WGS and bioinformatics analysis. Functional analysis of tet(X) was verified by cloning...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35107139
DOI: 10.1093/jac/dkab409

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