Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic diversity and characteristics of high-level tigecycline resistance Tet(X) in Acinetobacter species.

Genome medicine - 7 Dec 2020

Chen Chong, Cui Chao-Yue, Yu Jun-Jun, He Qian, Wu Xiao-Ting, He Yu-Zhang, Cui Ze-Hua, Li Cang, Jia Qiu-Lin, Shen Xiang-Guang, Sun Ruan-Yang, Wang Xi-Ran, Wang Min-Ge, Tang Tian, Zhang Yan, Liao Xiao-Ping, Kreiswirth Barry N, Zhou Shi-Dan, Huang Bin, Du Hong, Sun Jian, Chen Liang, Liu Ya-Hong

Abstract excerpt

BACKGROUND: The recent emergence and dissemination of high-level mobile tigecycline resistance Tet(X) challenge the clinical effectiveness of tigecycline, one of the last-resort therapeutic options for complicated infections caused by multidrug-resistant Gram-negative and Gram-positive pathogens. Although tet(X) has been found in various bacterial species, less is known about phylogeographic distribution and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acinetobacter
Share to Bayes Theorem

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flavobacteriaceae

Share to Genes, Bacterial

Share to Microbial Sensitivity Tests

Share to Tetracyclines

Share to Tigecycline

Share to Whole Genome Sequencing

Source

Open in PubMed Open full text

Identifiers

PMID: 33287863
DOI: 10.1186/s13073-020-00807-5
PMCID: PMC7722449

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic diversity and characteristics of high-level tigecycline resistance Tet(X) in Acinetobacter species.PMID 33287863Read ↗

Preliminary view of the global distribution and spread of the tet(X) family of tigecycline resistance genesSemantic proximity Read ↗

Source tracking and global distribution of the mobilized tigecycline resistant gene <i>tet</i> (X)Semantic proximity Read ↗

Co-Occurrence of tet(X4) and bla NDM-5 in Escherichia coli Isolates of Inpatient Origin in Guangzhou, ChinaSemantic proximity Read ↗

Phenotypic and genomic analysis reveals Riemerella anatipestifer as the potential reservoir of tet(X) variantsSemantic proximity Read ↗

Comparison of <i>tet</i> (X4)-containing contigs from metagenomic sequencing data with plasmid sequences of isolates from a cohort of healthy subjectsSemantic proximity Read ↗

Global dissemination of tet(X3) and tet(X6) among livestock-associated Acinetobacter is sporadic and mediated by highly diverse plasmidomesSemantic proximity Read ↗

Evolutionary Trajectory of the Tet(X) Family: Critical Residue Changes towards High-Level Tigecycline ResistanceSemantic proximity Read ↗

An Outbreak of tet(X6)-Carrying Tigecycline-Resistant Acinetobacter baumannii Isolates with a New Capsular Type at a Hospital in TaiwanSemantic proximity Read ↗

The ISVsa3-ORF2-abh-tet(X4) circular intermediate-mediated transmission of tigecycline resistance in Escherichia coli isolates from duck farms.Semantic proximity Read ↗

Emergence of plasmid-borne tet (X4) resistance gene in clinical isolate of eravacycline- and omadacycline-resistant Klebsiella pneumoniae ST485Semantic proximity Read ↗

Molecular Epidemiology and Mechanisms of Tigecycline Resistance in Clinical Isolates of Acinetobacter baumannii from a Chinese University HospitalSemantic proximity Read ↗

Low prevalence of mobilized resistance genes blaNDM, mcr-1, and tet(X4) in Escherichia coli from a hospital in ChinaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.