Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Presence of Mobile Tigecycline Resistance Gene <i>tet</i> (X4) in Clinical Klebsiella pneumoniae

9 Feb 2022

Abstract excerpt

Tigecycline, the first member of glycylcycline class antibiotic, is often considered one of the effective antibiotics against multidrug-resistant (MDR) infections. However, the emergence and wide distribution of two novel plasmid-mediated tigecycline resistance genes, tet (X3) and tet (X4), pose a great threat to the clinical use of tigecycline.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Mycobacterium research and diagnosis
Share to Pharmaceutical and Antibiotic Environmental Impacts

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35138117
DOI: 10.1128/spectrum.01081-21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Presence of Mobile Tigecycline Resistance Gene <i>tet</i> (X4) in Clinical Klebsiella pneumoniaePMID 35138117Read ↗

Emergence of plasmid-borne tet (X4) resistance gene in clinical isolate of eravacycline- and omadacycline-resistant Klebsiella pneumoniae ST485Semantic proximity Read ↗

Co-Occurrence of tet(X4) and bla NDM-5 in Escherichia coli Isolates of Inpatient Origin in Guangzhou, ChinaSemantic proximity Read ↗

Source tracking and global distribution of the mobilized tigecycline resistant gene <i>tet</i> (X)Semantic proximity Read ↗

Preliminary view of the global distribution and spread of the tet(X) family of tigecycline resistance genesSemantic proximity Read ↗

Plasmid-mediated tigecycline-resistant gene tet (X4) in Escherichia coli from food-producing animals, China, 2008–2018Semantic proximity Read ↗

Comparison of <i>tet</i> (X4)-containing contigs from metagenomic sequencing data with plasmid sequences of isolates from a cohort of healthy subjectsSemantic proximity Read ↗

Genetic diversity and characteristics of high-level tigecycline resistance Tet(X) in Acinetobacter species.Semantic proximity Read ↗

Earliest observation of the tetracycline destructase <i>tet(X3)</i>Semantic proximity Read ↗

Co-existence of a novel plasmid-mediated efflux pump with colistin resistance gene <i>mcr</i> in one plasmid confers transferable multidrug resistance in <i>Klebsiella pneumoniae</i>Semantic proximity Read ↗

Low prevalence of mobilized resistance genes blaNDM, mcr-1, and tet(X4) in Escherichia coli from a hospital in ChinaSemantic proximity Read ↗

Occurrence of Tetracycline Resistance Genes among Escherichia coli Isolates from the Phase 3 Clinical Trials for TigecyclineSemantic proximity Read ↗

AcrAB-TolC efflux pump overexpression and tet(A) gene mutation increase tigecycline resistance in Klebsiella pneumoniae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.