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Article

Low-grade oncocytic tumor of kidney harboring TSC/MTOR mutation: clinicopathologic, immunohistochemical and molecular characteristics support a distinct entity.

Virchows Archiv : an international journal of pathology - 1 May 2022

Zhang Hui-Zhi, Xia Qiu-Yuan, Wang Shu-Yan, Shi Meng-Jie, Wang Su-Ying

Abstract excerpt

Low-grade oncocytic tumor (LOT) has recently been described as a distinct renal tumor. LOT shows consistent morphologic features and a CK7-positive/CD117-negative immunophenotype. To examine the clinicopathological, immunohistochemical, and molecular features of LOT, we searched our institutional archives and identified seven cases of LOT. All patients were female, with a mean age of 66 years (range 44-79 years)....

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Source

Identifiers

PMID: 35099634
DOI: 10.1007/s00428-022-03283-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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