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Article

Concordance of MTOR Pathway Mutations and the Diagnosis of Renal Low-Grade Oncocytic Tumor (LOT).

International journal of surgical pathology - 1 Apr 2024

Siegmund Stephanie E, Al-Obaidy Khaleel I, Tsai Harrison K, Idrees Muhammad T, Akgul Mahmut, Acosta Andres M, Hirsch Michelle S

Abstract excerpt

The differential diagnosis for oncocytic renal tumors spans the spectrum from benign entities to more aggressive renal cell carcinomas (RCC). Recent work has characterized a provisional renal oncocytic neoplasm, namely the low-grade oncocytic tumor (LOT), which demonstrates overlapping morphologic features with oncocytoma and chromophobe RCC, but also has a unique immunoprofile (ie, diffusely positive for KRT7,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37357748
DOI: 10.1177/10668969231178032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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