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Cellular senescence in the cholangiopathies

24 Dec 2021

Abstract excerpt

PURPOSE OF REVIEW: Cellular senescence (i.e. permanent withdrawal from the cell cycle) is increasingly recognized as a pathologic feature in a variety of inflammatory liver diseases, including primary sclerosing cholangitis (PSC), primary biliary cholangitis (PBC) and additional cholangiopathies. Herein, we provide an update on the interplay between cholangiocytes, cellular senescence and the cholangiopathies....

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PMID: 35098933
DOI: 10.1097/mog.0000000000000805

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