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Article

MicroRNA regulatory networks associated with abnormal muscle repair in survivors of critical illness

28 Jan 2022

Abstract excerpt

BACKGROUND: Intensive care unit (ICU)-acquired weakness is characterized by muscle atrophy and impaired contractility that may persist after ICU discharge. Dysregulated muscle repair and regeneration gene co-expression networks are present in critical illness survivors with persistent muscle wasting and weakness. We aimed to identify microRNAs (miRs) regulating the gene networks and determine their role in the...

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PMID: 35092190
DOI: 10.1002/jcsm.12903

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