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DNA methylation alterations in muscle of critically ill patients

11 Mar 2022

Abstract excerpt

BACKGROUND: Intensive care unit (ICU)-acquired weakness can persist beyond ICU stay and has been associated with long-term functional impairment of ICU survivors. Recently, DNA methylation alterations were found in the blood of ICU patients, partially explaining long-term developmental impairment of critically ill children. As illness-induced aberrant DNA methylation theoretically could also be involved in...

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PMID: 35274472
DOI: 10.1002/jcsm.12970

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