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Article

Small RNAome profiling from human skeletal muscle: novel miRNAs and their targets associated with cancer cachexia

6 Jan 2017

Abstract excerpt

BACKGROUND: MicroRNAs (miRs) are small non-coding RNAs that regulate gene (mRNA) expression. Although the pathological role of miRs have been studied in muscle wasting conditions such as myotonic and muscular dystrophy, their roles in cancer cachexia (CC) are still emerging. OBJECTIVES: The objectives are (i) to profile human skeletal muscle expressed miRs; (ii) to identify differentially expressed (DE) miRs...

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PMID: 28058815
DOI: 10.1002/jcsm.12168

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