Article
Genetics of rheumatoid arthritis.
Mayo Clinic proceedings - 1 Jan 2006
Turesson Carl, Matteson Eric L
Abstract excerpt
Rheumatoid arthritis (RA) is a heterogeneous autoimmune disorder of unknown cause with variable clinical expression. About 70% of patients are women. Genetic factors play an important role and likely account for about 60% of disease susceptibility and expression. The association with the HLA-DRB1 gene is the best understood, although several non-HLA loci have been linked to RA, including the 18q21 region of the...
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