Article
Comprehensive Genomic Characterization of Upper Tract Urothelial Carcinoma.
European urology - 1 Oct 2017
Moss Tyler J, Qi Yuan, Xi Liu, Peng Bo, Kim Tae-Beom, Ezzedine Nader E, Mosqueda Maribel E, Guo Charles C, Czerniak Bogdan A, Ittmann Michael, Wheeler David A, Lerner Seth P, Matin Surena F
Abstract excerpt
BACKGROUND: Upper urinary tract urothelial cancer (UTUC) may have unique etiologic and genomic factors compared to bladder cancer. OBJECTIVE: To characterize the genomic landscape of UTUC and provide insights into its biology using comprehensive integrated genomic analyses. DESIGN, SETTING, AND PARTICIPANTS: We collected 31 untreated snap-frozen UTUC samples from two institutions and carried out whole-exome...
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