Article
A Photoannealed Granular Hydrogel Facilitating Hyaline Cartilage Regeneration via Improving Chondrogenic Phenotype.
ACS applied materials & interfaces - 14 Sept 2022
Zhu Yu, Sun Yi, Rui Biyu, Lin Junqing, Shen Junjie, Xiao Huimin, Liu Xuanzhe, Chai Yimin, Xu Jia, Yang Yunlong
Abstract excerpt
Hydrogel-based chondrocyte implantation presents a promising tissue engineering strategy for cartilage repair. However, the widely used elastic hydrogels usually restrict cell volume expansion and induce the dedifferentiation of encapsulated chondrocytes. To address this limitation, a photoannealed granular hydrogel (GH) composed of hyaluronic acid, polyethylene glycol, and gelatin was formulated for cartilage...
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