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Article

Serum progranulin is not associated with rs5848 polymorphism in Korean patients with neurodegenerative diseases.

PloS one - 1 Jan 2000

Jung Na-Yeon, Kim Hyang-Sook, Kim Eun Soo, Jeon Sumin, Lee Myung Jun, Pak Kyoungjune, Lee Jae-Hyeok, Lee Young Min, Lee Kangyoon, Shin Jin-Hong, Ko Jun Kyeung, Lee Jae Meen, Yoon Jin A, Hwang Chungsu, Choi Kyung-Un, Huh Gi Yeong, Kim Young-Eun, Kim Eun-Joo

Abstract excerpt

Low serum progranulin (PGRN) is known to be associated with granulin (GRN) gene mutation and T alleles of GRN rs5848 polymorphism. However, there have been only a few Asian studies exploring these. We investigated the serum PGRN levels, rs5848 genotypes, and their relations with cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarkers in the Korean population. Serum PGRN levels, GRN rs5848 polymorphism, and...

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Identifiers

PMID: 35085262
DOI: 10.1371/journal.pone.0261007
PMCID: PMC8794169

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